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COMPOCILLIN - a patient's guide


This medicine is often used to treat chest and throat infections. This article profiles the drug and its side effects.

DRUG NAME: Phenoxymethylpenicillin (Penicillin V)

USE: antibiotic - penicillin

This medicine is commonly used against chest and throat infections in children and adults. It acts by destroying the bacterial cell wall thus stopping its growth allowing your immune system to overcome the infection.

Since the introduction of penicillin antibiotics, some bacteria (e.g staphylococci) have evolved to produce penicillins. Penicillinase-producing bacteria have made a few antibiotics (including Compocillin-VK) less effective against certain infections. Therefore this medicine it is not indicated for these type of infections because of the risk of bacterial-resistance.


History of allergy to penicillins

Kidney impairment

Serious infections (unpredictable absorption)

Side effects:

Occasional: stomach upsets\t\t\t

Rarely: skin rash (discontinue treatment/discuss with doctor), bowel inflammation and blood disorders.\t\t


Excretion can be delayed by probenecid

Guar gum can reduce its absorption

Patient information:

  • Follow instructions carefully on the label
  • Always complete the course of antibiotics unless directed by your doctor
  • Food: Taken on an empty stomach (one hour before meals)
  • Alcohol: Little problems in moderation
  • Contact your doctor or seek urgent medical help if side effects are severe or ongoing, or your illness is worsening despite treatment.

See also:

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