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QUININE SULPHATE - a patient's guide


This medicine is used to treat night cramps, malaria and other infective species. This article profiles the drug and its side effects.


  • Q200
  • Q300
  • Quinoc-F
  • Quinoc-S

USE: night cramps

This medicine is mainly indicated for reducing the occurrence of nocturnal leg cramps, although it is also used against malaria, 'unknown' infective species and myotonia.

Its mode of action is unclear. It needs to be taken for up to 4 weeks until improvement may become apparent and then it must be taken regularly for continued benefit.


  • Atrial fibrillation
  • Kidney failure
  • G-6-PD deficiency
  • Optic neuritis and haemoglobinuria
  • Pregnancy and breastfeeding

Side effects:

  • ringing in ears
  • nausea, headache
  • blurred vision
  • hot flushes, confusion
  • blood disorders
  • skin rash
  • heart irregularities
  • convulsions (life threatening)

Seek urgent medical attention or contact Poisons Centre on (03) 4747000


May enhance effects of antiarrthymias, antihistamines (Teldane), antipsychotics, digoxin, anticoagulants, cisapride etc.

Patient information:

  • Follow the instructions on the label of this medicine.
  • Food: Take with food if it upsets your stomach.
  • Do not stop taking this medicine (at night) unless directed by your doctor.
  • During initial treatment, you should be monitored closely for side effects and dose response.
  • Contact your doctor or seek urgent medical attention if side effects are severe or ongoing.

See also:

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